Votrient 200mg - Anticancer drugs | view uses, side effects and price | MHP

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Votrient 200mg - Anticancer drugs | view uses, side effects and price | MHPDESCRIPTION Votrient (pazopanib) is a type of protein kinase inhibitors. It is also…
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Votrient 200mg - Anticancer drugs | view uses, side effects and price | MHPDESCRIPTION Votrient (pazopanib) is a type of protein kinase inhibitors. It is also indicated for the treatment of advanced kidney cancer and soft tissue sarcoma ď&#x201A;Ą Votrient 200mg is an antineoplastics medications which interfere with the development and spreadness of cancer cells in the body ď&#x201A;ĄSPREAD OF CANCERusage Votrient 200mg tablet is used as a single agent to treat the renel cell carcinoma and its advanced stage It works by preventing the activity of proteins which are interferes with the growth and spread of cancer cells. Votrient 200mg is also used as a single regimen to treat the Soft Tissue Sarcoma, (a type of cancer that occurs in the supportive tissue of the body). The cancer can develop in muscles, blood vessels, fat tissue or in other tissues that support, surround and protect organsMECHANISM OF ACTION Votrient 200mg tablet is an effective inhibitor of protein kinase and selective multiple receptor tyrosine kinases (RTKs) that are described in beginning of signal transduction pathways that ready for reproduction of tumor cells and affect processes critical to cell survival and tumor progression. Votrient 200mg RTKs comes in the blockage and involves the receptors for vascular endothelial growth factors (VEGFR-1, -2, and -3), platelet-derived growth factors (PDGFR-α and -β), and stem cell factor.PHARMACOKINETIC ABSORPTION Fast GI absorption with food and Bioavailability is 14-39%. Time of high plasma concentration: 2-4 hr. DISTRIBUTION bounding of human protein of pazopanib 200mg is >99%. METABOLISM Mainly in the liver pazopanib 200mg metabolized by CYP3A4 enzyme and to a lesser extent by CYP1A2 and CYP2C8 enzymes. ELIMINATION pazopanib primarily excreted through faeces approx 82%, 67% as unchanged drug and urine (<4%)with renal elimination. Terminal Elimination half-life: Approx 31 hr.PRODUCT DETAILS   Ingredients : Pazopanib Strength : 200mg Package : 30 TabletsDOSAGE AND ADMINISTRATION DOSAGE AND ADMINISTARTION Votrient 200mg tablet dosage for renal cell carcinoma and soft tissue sarcoma (cancer in joints, muscle) will be initially 800mg , the dose adjustment in 200mg increments or decrements dose based on tolerance but max dose in adult is 800mg/day.  Moderate total bilirubin >1.5 to 3 times, Votrient 200mg dose of 200mg once daily.  DOSAGE AND ADMINISTRATION Votrient 200mg tablet should be taken on a empty stomach (1hr before or 2hr after meals. Swallow the medicine whole don’t chew/crush. Food interaction :Avoid grapefruit juice or grapefruit juice. OVERDOSAGEoverdose of the drug can be upto votrient 200mg can be administrated and It is evaluated in clinical trials and treatment of overdose with votrient should consist of supportive measures and there is no specific antidote.DOSAGE AND ADMINISTRATION DOSAGE AND ADMINISTARTION Votrient 200mg dosage for renal cell carcinoma and soft tissue sarcoma (cancer in joints, muscle) will be initially 800mg , the dose adjustment in 200mg increments or decrements dose based on tolerance but max dose in adult is 800mg/day.  Moderate total bilirubin >1.5 to 3 times, Votrient 200mg tablet once daily. DOSAGE AND ADMINISTRATION Votrient 200mg should be taken on a empty stomach (1hr before or 2hr after meals. Swallow the medicine whole don’t chew/crush. Food interaction :Avoid grapefruit juice or grapefruit juice. OVERDOSAGEoverdose of the drug can be upto 2000mg can be administrated and It is evaluated in clinical trials and treatment of overdose with votrient 200mg tablet should consist of supportive measures and there is no specific antidote.SIDE EFFECTS Votrient 200mg has certain side effects, If any of the symptoms occrs or not cured then call the doctor immediately MAJOR SIDE EFFECTSDiarrhae; High blood pressure; low WBC; Elevated liver function test; Blood test abnormalities; increased in bilirubin levels. COMMON SIDE EFFECTSNausea; loss of appetite; fatigue; blood test abnormalities (low magnesium, low glucose); weakness, stomach ache.FOR MORE INFORMATION ADDRESS : Portion 'A' First Floor, Old No. 131, New No. 50, Pedariyar Kovil Street, Seven Wells, Chennai - 600001. Tamilnadu,India  PHONE NO : +91-9940472902  EMAIL: millionhealthpharmaceuticals@gmail.com  WEBSITE: https://millionpharma.com/pazopanib-200mg.php 
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