Tykerb 250 mg (Lapatinib)|novartis|uses,composition,side effects,price in India

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Tykerb 250 mg (Lapatinib)| novartis|uses,composition,side effects,price in IndiaDESCRIPTION Tykerb 250mg belongs to class of antineoplastic drugs which prevents…
Tykerb 250 mg (Lapatinib)| novartis|uses,composition,side effects,price in IndiaDESCRIPTION Tykerb 250mg belongs to class of antineoplastic drugs which prevents the development and spreading of cancer cells all over the body.  Tykerb 250mg tablet is indicated for metastatic breast cancer and spreading after using of other chemotherapy drugsINDICATION Tykerb 250mg tablet  with combination of capecitabine is indicated for the treatment of advanced breast cancer after the failure of other cancer medicine. Tykerb 250mg is also combined with letrozole is indicated for the treatment postmenopausal women with hormone receptor positive metastatic breast cancer.MECHANSIM OF ACTION Tykerb 250mg is a type of classification called kinase inhibitor and act by intracellular tyrosine kinase.  Tykerb 250mg  prohibits ErbB-forced tumor cell growth in vitro and in various animal models. When combination 5-fluracil with  Tykerb 250mg tablet  created an additive effect in the 4 tumor cell lines tested. Development inhibits the  Tykerb 250mg tablet tablet effect were examined  in trastuzumab-conditioned cell lines. MECHANSIM OF ACTION Tykerb 250mg tablet provide selective action against breast cancer cell lines selected for long-term growth in trastuzumab-containing  intracellularly. Hormone receptor-positive breast cancer cells (with ER [Estrogen Receptor] and/or PgR [Progesterone Receptor])  that co express the HER2 bear Tykerb 250mg to be protection against established endocrine therapies. Synchronously  hormone receptor-positive breast cancer cells that initially lack EGFR or HER2 unrecalled these receptor proteins as the  tumor becomes resistant to endocrine therapy.PHARMACOKINETIC ABSORPTION Poor absorps from the GI tract. peak plasma concentration is approx 4hrs ; bioavailability is 95%. Tykerb 250mg with foodwill increase the systemic exposure.  DISTRIBUTION Plasma protein binding is 99%  METABOLISM Tykerb 250mg tablet Metabolized mainly by CYP3A4 and CYP3A5.  ELIMINATION The drug eliminated dose via feces more than 14% and <2% urine.  Eliminated half life is 24hrs.PRODUCT DETAILS Brand : Tykerb  Ingredients : Lapatinib  Strength : 250mg  Manufactured : Novartis India Ltd  Package : 30 TabletsDOSAGE AND ADMINISTRATION DOSAGE AND ADMINISTRATIONThe usual dose of Tykerb 250mg tablet  for adult suffering HER2 positive metastatic breast cancer  (with xeloda) is 1250mg once daily for 1-21days continuously repeating. Femara Combination with  Tykerb 250mg the doserecommended is 1500mg orally once a day continuosly once daily every day. Take the drug Tykerb 250mg  tablet on an empty stomach(1hr before or 1hr after). OVERDOSEIf overdose occurs, seek to emergency department or call poison control helplineSIDE EFECTS SIDE EFFECTSTykerb will cause mild to moderate side effects in patients. Tykerb 250mg tablet If symptoms causes serious the inform the doctor as soon as possible. COMMON SIDE EFFECT OF TYKERB 250MG TABLETSLumbar pain; diarrhae; dry skin; nail of finger toe changes; headache; in digestion problem ; decreased appetite; mild hair loss or thinning;  mouth ulcers; Tykerb 250mg tablet nausea; nosebleed; redness and hands and feet will have tingling; weakness; insomnia; vomiting.SIDE EFFECTS SERIOUS SIDE EFFECT OF TYKERB 250MG TABLETS Severe tightness; difficulty in breathing; unusual bruising or bleeding; Tykerb 250mg tablet unusual itching; yellowing of the eyes or skin;.  Chest pain; urine will be dark; dizziness or lightheadedness; Rapid or irregular heartbeat; pale stools; persistent loss of appetite;  severe or persistent cough; severe or persistent diarrhea,  nausea, vomiting and skin allergy Tykerb 250mg like itching, rashes, blisters in mouth, face, lip or tongue.SAFETY PRECAUTIONS SAFETY PRECAUTIONSIf you are allergic to lapatinib, then do not use the drug If you had hepatic problem, cardio disease, an electrolytic imbalance then discuss with doctor whether it’s safe to use or not piror to Tykerb 250mg  treatment. While patients during pregnancy, it should strictly avoid the drug because it harm the unborn baby or cause birth defects. There is not known whether Lapatinib passes into breast milk. Hence avoid breast feeding to the infants during  Tykerb 250mg tablet treatment,FOR MORE INFORMATION   ADDRESS : Portion 'A' First Floor, Old No. 131, New No. 50, Pedariyar Kovil Street,  Seven Wells, Chennai - 600001. Tamilnadu,India PHONE NO :  +91-9940472902 EMAIL : millionhealthpharmaceuticals@gmail.com Website:https://millionpharma.com /lapatinib-250mg.php
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