kex2 protease

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S. cerevisiae Active KEX2 protease protein (aa 114 - 667) (DAG-P2974) This product is for research use only and is not intended for diagnostic use.PRODUCT…
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S. cerevisiae Active KEX2 protease protein (aa 114 - 667) (DAG-P2974) This product is for research use only and is not intended for diagnostic use.PRODUCT INFORMATION Product OverviewActive S. cerevisiae KEX2 protease protein fragmentAntigen DescriptionKex2 in the yeast Saccharomyces cerevisiae is a transmembrane, Ca2+-dependent serine protease of the subtilisin-like pro-protein convertase (SPC) family with specificity for cleavage after paired basic amino acids. At steady state, Kex2 is predominantly localized in late Golgi compartments and initiates the proteolytic maturation of pro-protein precursors that transit the distal secretory pathway. However, Kex2 localization is not static, and its itinerary apparently involves transiting out of the late Golgi and cycling back from post-Golgi endosomal compartments during its lifetime.NatureRecombinantExpression SystemHi-5 cellsSpeciesS. cerevisiaePurity> 95 % by SDS-PAGE.Purity is greater than 95% by SDS-PAGE gel and HPLC analyses.ConjugateUnconjugatedApplicationsSDS-PAGE FuncSMolecular Weight60 kDaReconstitutionThe lyophilized protein is stable at room temperature for up to 1 month. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C.Cellular LocalizationGolgi apparatus; trans-Golgi network; trans-Golgi network membrane; single-pass type I membrane protein.Bio-activityActive S. cerevisiae KEX2 protease protein fragment from High-5 insect cells contains the same specific activity and recognition sequence specificity as yeast derived KEX2. 1 milligram of recombinant KEX2 contains activity equivalent to at least 40 unitsFormatLyophilisedBufferPreservative: None Constituents: 5mM Calcium chloride, 10mM Sodium acetate, pH 6.0StorageShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw45-1 Ramsey Road, Shirley, NY 11967, USA Tel: 1-631-624-4882 Fax: 1-631-938-8221Email: info@creative-diagnostics.com 1© Creative Diagnostics All Rights Reservedcycles.BACKGROUND IntroductionSaccharomyces cerevisiae is a species of yeast. It is perhaps the most useful yeast, having been instrumental to winemaking, baking, and brewing since ancient times. It is believed that it was originally isolated from the skin of grapes (one can see the yKeywordsKEX 2; Kex2p; QDS1; SRB1; VMA45; S. cerevisiae KEX2; Saccharomyces cerevisiae KEX245-1 Ramsey Road, Shirley, NY 11967, USA Tel: 1-631-624-4882 Fax: 1-631-938-8221Email: info@creative-diagnostics.com 2Š Creative Diagnostics All Rights Reserved
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